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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '6fd638c8b407df7fa6f6eeadc9e1b4c6869eb4a115b47c5353856d3d13cbe294' 
  AND token = '4+J3R+FfZRxj4L+PHn8/OFOhcQI394271RjCfgaywM4=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00026

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}