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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'c4dd6157268234eff212e28faa0d5f54c676194d742e2abcad5294ee285cbe76' 
  AND token = 'meMcrXBW7FrBpER9s0afOLu1T4MAtw8rzoCTmDPaySI=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00046

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}