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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'b00eed2074b25d239de1cd5f378fa4cba3d499258ab8fe5b2235dd3d8e8602ce' 
  AND token = 'ctkUch0KWqkj4uzigrQkKWqeUueQO8B/ExxQYINP2Y4=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00059

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}