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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '1b63036d3ae1c3cde6ae445d32263f30a7322f6003dc0e2aab1eb2e663b131cc' 
  AND token = '8REMSH5FWPa0I7faygUUuGqmlaJpej/tdwZgrgRu7Ck=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00031

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}