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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '17f264875a9917e044d82d927356ea4b860a11d3a6f6e8e5d3d7ea898f409516' 
  AND token = 'AV4NJ/WHcDA3NofhnXtyhfunDLe+/NJiGFLTRp5sAyo=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00054

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}