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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '3cd6f45612667efaa7ad57275e9c22202ff5c875a851cb2d6299fefbd8923199' 
  AND token = 'guukB/5NCjzn3fduVwBaEasu7rmah8CQW4UJ5hZf9kU=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00020

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}