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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'e9f43bd93f4c79b1bd787f3faadbfa5b75e2bfff5d4f5fbdff3a8836fc4241c0' 
  AND token = 'tYQveFM9WlCDdjD6IKIuO6kcUMGXHREFh5GH5zIYL3s=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00020

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}