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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '9864c46a50eb0c2fe27634e059bfe9ee54d4e4ea7763f8180ce3c74b0bd123fe' 
  AND token = 'P1m+5U+IfbiQS8fjUg0sx4JS9xqvmsUFtOc7w+ye4Pc=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00025

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}