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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '6018cd6204e12860501f8a0b13ac3d304fa1de496a3bf9bb16c2ab1818e2e008' 
  AND token = 'jLnCIe7LTuoLYqsucQo209/4oUeXdGousu66XWcM6Yc=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00021

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}