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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '4ae9b1b6dfe35b50cb883be24759af075e3e4f4df255aabae778f8695b333373' 
  AND token = 'CQ8YNqGTJV6awkQvll/yYT/AElR61fpTzDiseFRUBH8=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00025

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}