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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '0b764399865f6c5d38af7b13286231fd19af8b72fffd89abbddfa65cef47b03d' 
  AND token = 'GqosXjI49ygH+9+MZdBRdreUm69Fr+uWZ0u5Lo5oSa4=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00019

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}