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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '0165758864552bfaf08fd81ee8e9c070d5eff551c219bfbc70b6ee80bb31e107' 
  AND token = 'MbbMgEp2EAdhCh+g62TlGNkBbuJEXesgXSzNlpGEnOE=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00024

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}