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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '43d5e0c1338fd04877af8630ef689e72a23eab63d32fdbabcbab93ed2e74180d' 
  AND token = 'GdoYnkYB6xZN4utBmWV4mnE6JsRXD9QVqVV/ueduuXM=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00019

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}