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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'a6018c7a6d24f29b21417c0714c946588f7d586abe60c0d3905e7d44d2a52274' 
  AND token = 'bBErO8NrNa3M5nZqnjQVya04nIzCZobxVz90RN6cBg8=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00026

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}