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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '4750d4d316492e40825c65519f8bfc64b75f251989d8aa372eff16a703b001de' 
  AND token = '2ulkl9NiSKmdNWw3hWe/EDapHFyonz7E9OJzje3elEc=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00022

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}