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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'd6f2a0c319b3102ab8f65106e8013f5eb1c1e3cb14cfa5eb068494c9f3ce6385' 
  AND token = 'XdOZRW4chpMboclpChclf1QGtl/R70vIq7OMH98u/GE=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00024

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}