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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '787c7cdff0437ed956b600be6504034557c1e884ae1e04d29b36fb5adbfd993e' 
  AND token = 'nUx10pYD4f7sUZzdJbobaEPaazymeL01NeS58007LbA=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00025

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}