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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '33ffe26abd8be2943b218a69a999b15c7871b60489b7c28e43ab668a0259e63e' 
  AND token = 'MPel8+tU4fXebvze52c81APQk4c+q3NAb2l57ttWdjw=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00026

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}