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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '7549b09a1cf105b6fa46a5d54a0aa090dcb53258c81ea40fb088bab8d43f9dd8' 
  AND token = '0f/meZK1CY11hrVZvoEEyl3kc4gbBwBhHgUifJOIr9c=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00023

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}