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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'c291e9ae2712489e0ace8db097effbec8c33b450ac9bbb77c876a4c4bed9cc60' 
  AND token = 'cSvH+8aicg5gSlINF7IJo1SuV9JQBrAZ3tHyiYyM3hg=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00030

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}