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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'e3c7080cec07a8c8e887eb6e960a1f013ecd7574464fca8b4a57801a2d299221' 
  AND token = 'QJ6no70hyOBThqGskmkcntK++BqPpntcSQeA4e74MPA=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00037

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}