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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '5e18478474dbd11144c34ec37418da1059851adf42e0ea8dda16ef8931814f6a' 
  AND token = 'aC74h3gZpDus0noooPtQLnvExOnd61aZ7ZNxyOoVnSI=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00028

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}