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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '4bba59c83ba9d621b07971e6e2af71b56b09325567976fc7b7d5d687c18171f0' 
  AND token = 'hMP0vKFP27RRitx08VYfxKc9RYyTAxA1TWQyorleUY8=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00027

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}