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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'bbce50b7f7ec59d1a50882a181843ebf9ac7229b834f2236f74654562962ea16' 
  AND token = 'ob9mBTCPvE7XFhV4hdZCQ7srcwNumaQ56iO+2VKhpI0=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00028

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}