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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '0d95c277bdb5c5cf10bcb6c93e1143f345addfd9fe04fe27344c0fbd3a5c5110' 
  AND token = 'Rcv946FKGbAGbh1UWBs2uKJ6B3sJ7B8uJBypSa83iD8=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00035

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}