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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'a6e67f2590458aa09b1aec3ff7e9562fde68b0f400b90b3a22d6effa673c3e74' 
  AND token = 'QThRkh3yzZA4wDGxDFZYp7NnZrTgNUVfb8LCVzbb01Y=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00019

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}