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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'ccd33b7fbe048768c9e434d4440fd74cf1c02c117c0a8cc788d9a1ed5a69654a' 
  AND token = 'iUFaLW0OF2ZoC+OJMTfFJ6/I2gC2gGAJ05Sp42ZGUhw=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00019

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}