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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'c89d0dcb650e5bc27517505ab816875b265179db4e0ebdc82c1d7deae8515898' 
  AND token = 'TxIJRevWDPw+gBEXIbPk62kS6eIEs4dJzL8UUWh9BWc=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00017

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}