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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '65dc6f52aa0715e2d044501637d656c6f9adc8e7fdb2f57eb3a7301c2512727f' 
  AND token = 'z15yOt+nJB/sAj14p2YMIT0mXuKMJoDdyCpYo/o1+hA=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00029

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}