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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '7e0610a9d751e80a0315c195c357e81e802b9df8d985d3194e74e8a78691a526' 
  AND token = '2MwApttKF2tnrxeo9+O/Ls3GZ79uz6Uaosssjh49EZk=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00035

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}