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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '052033543862ed4c1c1992c4c6cd29db44c6ee4b3bfe7fe3f4fa46464abbf8a4' 
  AND token = 'ZfO/Ou5EPvTGGwekGwd/amNeNQg37DzwapZ2hnW3jNU=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00018

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}