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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '42565af18cdec2bb95141f96194a536d50bf8e113a12f68a9252db99288a9fa2' 
  AND token = 'i+xsiUih3Rx3C8oyFD5GCnsfvxF4M5CtV618ZFXCHUs=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00022

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}