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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '3d3078a0a900867b728d9bf6e735bbdea4f11982328db370363a0be40deef880' 
  AND token = 'TySDEkTG7eFGxBVWCaM2PgRK5hXXm4fAuYODeoREMTQ=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00030

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}