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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '7f6da295cc21f4f2b975e381dfb242495eecdb7eb6f680c89ea34a6ece6cf44e' 
  AND token = 'uxLExkwGvm8D6vVuLyezyWqqw4xXLkQSDxPTFQ8Rhvs=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00036

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}