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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '52acabd75cf469c6817f1ed3eefa6d3d95afc8231a272a641c2eeba7b8bd9669' 
  AND token = 'vE3JGPIVVJLawluZzzCtpc2xFw1FSc9C5GcB51aTouQ=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00021

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}