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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'd11a148712452458dfa749d82cf441175aad545dda0b550e2017dd8a5332f5c1' 
  AND token = 'LeO6kF9npjh4hktobt4Z7Kj4YOT2N7iZRRfZYOBz1dY=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00025

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}