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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '0b5bd205ebe15ec7a202c76354be1c2df629934ff77fe2724732b8647db642fe' 
  AND token = 'JV31bZmtiRAjKV5Pxa9FdARd/4WaYWwibpgZzZ9fKzs=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00039

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}