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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'e54d90818fd510471f11e8859894109fdf3e84c6dfbf7a5a7906dc5b92285728' 
  AND token = 'SbaIo5bwMUZthO27joxer1B6nMpu5JyHyGMamvfRrEg=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00032

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}