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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '7da9de44005f016b1005b714ddf5128ab4266780841d72f41af86ce2421d7d36' 
  AND token = 'IBbJRwDCm+fRqoBMqoRm4HVdS0KiryLBUyiQCjJp6h4=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00028

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}