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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'd615a554393ed698cd3f7184fd0dde2e316da523a4c3a73aa97280a4821e0f47' 
  AND token = 'fYvTk2xoW75yrxnUS4KbxGeJPbKi2y7g51uRBRNX5mc=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00034

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}