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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '1681aaf9847a844b57043daeca48204428728baaa09b28ac33260c50e8491423' 
  AND token = 'ukW3bY7RR12jx2FQOnDTDEErHI+dwOH0cCAea2O7aKc=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00024

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}