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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '157df986a1624765fc47ff0ccc8cec0bb3e5f1f14b0d366d3a5e5a62888890ce' 
  AND token = 'GZV4REfc/SiosOrdCNO1n4x+mYcm346xcpFDwid+5vw=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00023

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}