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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'c6f8185e935f4f8b09a04298d22c487587f537aba3d400e64be07bd96fa1ed5e' 
  AND token = 'Ix6VN6MmJNqKoJltIRODSmJCUx2yXcDD/A3MYDkIi0c=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00028

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}