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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '762c7e8c4e7226bb3054476b41c2d6b7f83f1b2448d72ebacbf382378745c520' 
  AND token = 'u95el0rOr8KcqJZiyX9SXA9eKbQxyyXAZD6y4OlpFIc=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00036

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}