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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '6791520acd6d4a5b8fac7d5f5d3e6927fb8cf3632d27f43c626429c851da1e42' 
  AND token = 'jQrmD4NnP61SCghiodySydqcbrXtK9yXu6Rb1o0GLOg=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00025

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}