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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'af26352524656e45324cdb374e373acca33758019483093452b1f2217b64a149' 
  AND token = 'dCs9YWx3cyldbS4lFshHT5+6hvmelE1st5W2vrq1GJ8=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00029

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}