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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '950ef4e4ae60a7d751f423b7ea8d14d0d1f568ec5e5b026b94a5a66678df676f' 
  AND token = 'C46m7LlkPP5nIePylObdp6OaBK9Tgg9HX0fO1luvcwg=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00019

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}