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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'da378cc2292996da2683cc6dd654bec38bb52dd3374d2524adb64e0ea7eb37a5' 
  AND token = '8f2tlqDM2TN5rR5b9ZCXtM6BaS9kPUGPDrgA10KE+1g=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00023

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}