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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '721dbc1450a1cb91b9329d0119655c118425002091c89f5ed778e5e7ae028598' 
  AND token = 'KYYxXZXi6nSmwy6nT5vaYFa3oG81EiqbAj+Mzb3x+xA=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00031

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}