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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'e8d639123da893e0fd8536b6cf2a73851158e7018d865bf756c062ae9d5dad3b' 
  AND token = 'BOTc4B1DbQ8WaTuMzf7aKHxOO2pXtvPkgUQNTdo6/pU=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00031

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}